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In vitro research has demonstrated that hCG decreases TIMP-1 secretion in endometrial stromal cells, thereby facilitating extravillous trophoblast invasion with MMP-2 levels increasing and gelatine zymography confirming increased MMP-2 activity following hCG treatment

The VEGFR2 signaling pathway Vascular Endothelial Growth Factor Receptor 2, or VEGFR2, is a primary regulator of blood vessel formation

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It is especially useful in conditions where oral supplementation is not suitable or effective, such as in critically ill patients, ICU cases, severe vomiting, or in patients with poor compliance to oral therapy

2017 Jun;6(6):2222-2225 Kulshreshtha B, Pahuja I, Kothari D, Chawla I, Sharma N, Gupta S, Mittal A